In a study, Mitragyna Speciosa supplementation suppressed hunger and blocked the hypothalamus, the area of the brain responsible for cravings and appetite. It remains to be seen if the same effects occur in humans. More studies are needed to determine exactly how this drug affects appetite and cravings in humans. In the meantime, maeng da kratom is a promising treatment for the management of appetite. However, there are some possible side-effects. 

Susceptible to side-effects 

There are some possible side-effects associated with Mitragyna Speciosa. While it is not illegal, there are a number of precautions you should take. The FDA and the U.S. The Drug Enforcement Administration (DEA) regulates Mitragyna Speciosa. Abrupt withdrawal from Mitragyna Speciosa may cause a number of side-effects, including aggression and hostility. Users may also experience jerky limb movements or muscle and bone pain. People may also become confused and have hallucinations. 

Among the side-effects of Mitragyna Speciosa, a common concern is possible addiction. The psychoactive ingredient mitragynine may cause dependence. This can result in sweating, tremors, nausea, hallucinations, and inability to sleep. In addition, the production of Mitragyna Speciosa is not regulated by the FDA. Additionally, there are no established standards for safe production. Despite reports of positive effects, more research is needed to establish the safety of Mitragyna Speciosa for long-term use. 


The effectiveness of Mitragyna Speciosa in controlling appetite is a debated issue in Western research. A recent study by the FDA analyzed a large number of studies conducted in the Eastern world, and found that it did have positive effects on appetite. The study also utilized computerized algorithms developed by the FDA for its own research. While the study was anecdotal, the positive effects of Mitragyna Speciosa were noted by many of its users. 

The study included a review of more than 500 YouTube videos describing Mitragyna Speciosa use and found that it was widely used for treating opioid dependence, insomnia, erection problems, and other psychological issues. Most users described their experience with Mitragyna Speciosa as positive, but some reported that it had side effects, such as loss of motivation or drowsiness. It is unknown whether Mitragyna Speciosa is effective for treating appetite, but it was widely used in religious ceremonies, and is a legal alternative to drinking alcohol. 

Side-effects of Mitragyna Speciosa 

Mitragyna Speciosa is not a good option for people with high blood pressure or heart disease. While it does help reduce the effects of obesity, it does come with some risks. It can be dangerous for breastfeeding women, pregnant women, and people with a history of depression. It can worsen existing mental health conditions and increase the risk of suicide. In high doses, Mitragyna Speciosa can lead to death. In fact, 44 people died after taking Mitragyna Speciosa in 2017. 

Constipation is a common side-effect of Mitragyna Speciosa use, and can be painful. If this occurs frequently, it can be a sign of another medical condition. Mitragyna Speciosa addiction can also lead to a decrease in appetite and a substantial amount of weight loss. People with Mitragyna Speciosa addiction may even develop anorexia nervosa, a condition in which individuals severely restrict their calorie intake. While these effects may seem harmless, they can lead to serious health issues. 

In addition to promoting weight loss, Mitragyna Speciosa has many other side-effects. Long-term users may become addicted to it. Because it activates opioid signaling in the brain, it can produce a dependency like the effects of heroin and oxycodone.  


The effects of kratom extracts for appetite management are generally positive. In studies, rats fed with Mitragyna Speciosa had reduced appetite and body weight, while more than one dose had analgesic properties. However, some side-effects of Mitragyna Speciosa use should be noted. It is important to note that Mitragyna Speciosa is not a treatment for obesity, and should be used over a long period of time. 



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